/

/

含脂脂的微流体生产-温度敏感脂质体

JoVE Journal
Bioengenharia

É necessária uma assinatura da JoVE para visualizar este conteúdo. Faça login ou comece sua avaliação gratuita.

JoVE Journal Bioengenharia

Microfluidic Production of Lysolipid-Containing Temperature-Sensitive Liposomes

Please note that all translations are automatically generated. Click here for the English version.

含脂脂的微流体生产-温度敏感脂质体

DOI:

10.3791/60907-v

•

09:51 min

•

March 03, 2020

•

Calvin C. L. Cheung, Guanglong Ma, Amalia Ruiz, Wafa T. Al-Jamal

¹School of Pharmacy,Queen’s University Belfast

Capítulos

00:05Introduction
01:06Equipment Setup
02:46Lysolipid-Containing Temperature-Sensitive Liposome (LTSL) Preparation
04:48Remote Doxorubicin (DOX) Loading
05:48Laser Heating and Triggered Release
07:13Results: Representative LTSL10 Characterization, Loading, and Photothermal Heat Triggering
08:59Conclusion

Summary

Tadução automática

该协议提出了使用交错的刺骨微流体器装置制备热敏脂质体的优化参数。这还允许将多索鲁比辛和丁氨酸绿色共同封装到脂质体中，并产生光热触发的多索鲁比素释放，用于控制/触发药物释放。

Tags

Keywords: Microfluidics Liposomes Temperature-sensitive Liposomes Drug Delivery Doxorubicin Indocyanine Green Syringe Pumps Micromixer Lipid Mixture Ammonium Sulfate

Article

Embed

ADICIONAR À PLAYLIST

Usage Statistics

Vídeos Relacionados

微流体技术，探讨细胞变形

生产和目标单价量子点

在脉冲激光激发金纳米粒子集成光电响应脂质体及其微泡空化的测量的合成

治疗的siRNA递送至CNS使用阳离子和阴离子脂质体

多级可变高度的光刻多层带瓣微流体装置

含脂肪酸脂质体的制备、纯化及应用

定量荧光显微镜为基础的单脂体测定，用于检测单个脂质体之间的成分不均匀性

使用无细胞细菌提取物、脂质体和乳液转移制备蛋白质生成合成细胞

荧光染料标记脂质体体内组织特异性细胞摄取的制备、给药和评估

模仿神经血管化初始事件的微流体模型

Read Article