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A Minimally Invasive Method for Intratracheal Instillation of Drugs in Neonatal Rodents to Treat Lung Disease
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Medicina
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JoVE Journal Medicina
A Minimally Invasive Method for Intratracheal Instillation of Drugs in Neonatal Rodents to Treat Lung Disease

A Minimally Invasive Method for Intratracheal Instillation of Drugs in Neonatal Rodents to Treat Lung Disease

DOI:
10.3791/61729-v

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04:21 min

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August 04, 2021

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, ,
1Department of Pediatrics,Case Western Reserve University

Capítulos

  • 00:04Introduction
  • 01:08Intratracheal Instillation (ITI) and Characterization Post Administration
  • 03:07Results: Validation of Intratracheal Instillation Technique
  • 03:50Conclusion

Summary

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Tadução automática

This technique of instilling drugs directly into the trachea of neonatal rodents is important in studying the impact of locally administered drugs or biologicals on neonatal lung diseases. Additionally, this method can also be used for inducing lung injury in animal models.

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Keywords: Minimally InvasiveIntratracheal InstillationNeonatal RodentsLung DiseaseAnesthesiaTracheaVocal CordsSyringePipetteVisual Assessment

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