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研究癌症转移至肺部的永久窗口

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JoVE Journal Pesquisa do Câncer

A Permanent Window for Investigating Cancer Metastasis to the Lung

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研究癌症转移至肺部的永久窗口

DOI:

10.3791/62761-v

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07:06 min

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July 01, 2021

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Lucia Borriello*^1,2, Brian Traub*^1,2,3, Anouchka Coste^2,3, Maja H. Oktay^2,4,5, David Entenberg^2,4

¹Department of Anatomy and Structural Biology,Einstein College of Medicine / Montefiore Medical Center, ²Gruss-Lipper Biophotonics Center,Einstein College of Medicine / Montefiore Medical Center, ³Department of Surgery,Einstein College of Medicine / Montefiore Medical Center, ⁴Integrated Imaging Program,Einstein College of Medicine / Montefiore Medical Cente, ⁵Department of Pathology,Einstein College of Medicine / Montefiore Medical Center

Capítulos

00:04Introduction
00:59Lung Window Surgery
04:46Results: Assessment of Tumor Cell Migration
06:02Conclusion

Summary

Tadução automática

在这里，我们提出了一种用于为小鼠胸部手术植入永久留置光学窗口的方案，该方案可实现高分辨率的肺活体成像。窗口的持久性使其非常适合研究肺部的动态细胞过程，特别是那些缓慢进化的过程，例如播散性肿瘤细胞的转移性进展。

Tags

Keywords: Cancer Metastasis Lung Metastasis Tumor Cell Colonization Tumor Dormancy In Vivo Real-time Monitoring Pulmonary Diseases Intubation Rib Cage Incision Lung Window Implantation Purse-string Suture

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