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Establishing a Device for Sleep Deprivation in Mice
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JoVE Journal Medicina
Establishing a Device for Sleep Deprivation in Mice

Establishing a Device for Sleep Deprivation in Mice

DOI:
10.3791/65157-v

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05:05 min

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September 22, 2023

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, , , , ,
1Department of Cardiology,The First Affiliated Hospital of Bengbu Medical College, 2Department of Cardiology, Ren Ji Hospital, School of Medicine,Shanghai Jiao Tong University

Capítulos

  • 00:00Introduction
  • 00:43Preparation of the Sleep Deprivation Device for Mice
  • 02:44Induction of Sleep Deprivation in Mice
  • 03:32Results: Evaluation of Pathophysiological and Metabolic Changes Associated with Sleep Deprivation in Mice
  • 04:36Conclusion

Summary

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Tadução automática

The present protocol outlines a method for setting up a cost-effective rocker platform-based device used for inducing sleep deprivation in mice. This device has proven to be effective in causing disruptions in electroencephalogram (EEG)-evidenced sleep patterns, as well as inducing metabolic and molecular changes associated with sleep deprivation.

Tags

Sleep DeprivationMouse ModelRocker PlatformAutomated DeviceCost-effectiveMinimally StressfulMotorConnecting RodPlastic ContainerWater BottleTime Contactor

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