Chapter 13
Genomes and Evolution
![Evolutionary Relationships through Genome Comparisons](https://cloudfront.jove.com/files/media/science-education/science-education-thumbs/11987.jpg)
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome…
![Genome Copying Errors](https://cloudfront.jove.com/files/media/science-education/science-education-thumbs/11988.jpg)
DNA replication is a well-evolved process that copies millions of base pairs with high fidelity during each cell division. Occasionally a wrong base…
![Synteny and Evolution](https://cloudfront.jove.com/files/media/science-education/science-education-thumbs/11990.jpg)
John H. Renwick first coined the term “synteny” in 1971, which refers to the genes present on the same chromosomes, even if they are not…
![Multi-species Conserved Sequences](https://cloudfront.jove.com/files/media/science-education/science-education-thumbs/11991.jpg)
Next-generation sequencing technologies have created large genomic databases of a variety of animals and plants. Ever since the human genome project…
![Exon Recombination](https://cloudfront.jove.com/files/media/science-education/science-education-thumbs/11993.jpg)
The evolution of new genes is critical for speciation. Exon recombination, also known as exon shuffling or domain shuffling, is an important means of…
![Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin](https://cloudfront.jove.com/files/thumbs/56684_t.png)
Phylogenetic analysis uses nucleotide or amino acid sequences or other parameters, such as domain sequences and three-dimensional structure, to…
![An Array-based Comparative Genomic Hybridization Platform for Efficient Detection of Copy Number Variations in Fast Neutron-induced <em>Medicago truncatula</em> Mutants](https://cloudfront.jove.com/files/thumbs/56470_t.png)
Mutants are invaluable genetic resources for gene function studies. To generate mutant collections, three types of mutagens can be utilized,…
![Infinium Assay for Large-scale SNP Genotyping Applications](https://cloudfront.jove.com/files/thumbs/50683_t.png)
Infinium Assay for Large-scale SNP Genotyping Applications
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Genotyping variants in the human genome has proven to be an efficient method to identify genetic associations with phenotypes. The distribution of…