Chapter 39
Stem Cell Biology And Renewal in Epithelial Tissue
![Zygotic Development And Stem Cell Formation](https://cloudfront.jove.com/files/media/science-education/science-education-thumbs/13461.jpg)
The development of all multicellular organisms starts with the fusion of haploid cells called sperm and egg to form a diploid zygote. A zygote is a…
![Source And Potency Of Stem Cells](https://cloudfront.jove.com/files/media/science-education/science-education-thumbs/13462.jpg)
Stem cells are undifferentiated cells with extensive self-renewal properties that help them maintain their population during the fetal and adult…
![Renewal of Intestinal Stem Cells](https://cloudfront.jove.com/files/media/science-education/science-education-thumbs/13464.jpg)
The intestinal epithelial lining rapidly renews every 4 to 5 days. The renewal is facilitated by intestinal stem cells (ISCs) located at the base of…
![Role of Ephrin-Eph Signalling in Intestinal Stem Cell Renewal](https://cloudfront.jove.com/files/media/science-education/science-education-thumbs/13465.jpg)
Erythropoietin-producing hepatocellular carcinoma receptor (Eph) and its ligand, Eph receptor-interacting protein (Ephrin) were first discovered in…
![Renewal of Skin Epidermal Stem Cells](https://cloudfront.jove.com/files/media/science-education/science-education-thumbs/13466.jpg)
The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly…
![Multipotency and Niche of Bulge Stem Cell](https://cloudfront.jove.com/files/media/science-education/science-education-thumbs/13467.jpg)
A hair follicle or HF is a small part of the skin that produces the hair shaft. Paul Gerson Unna was the first to observe a bulge in the human hair…
![Distinctive Features of Adult Stem Cells vs Cancer Stem Cells](https://cloudfront.jove.com/files/media/science-education/science-education-thumbs/13469.jpg)
A stem cell is an unspecialized cell that can divide without limit as needed and can, under specific conditions, differentiate into specialized…
![Stem Cell Culture](https://cloudfront.jove.com/files/media/science-education/science-education-thumbs/13470.jpg)
Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and…
![Intestinal Stem Cell Isolation and Culture in a Porcine Model of Segmental Small Intestinal Ischemia](https://cloudfront.jove.com/files/thumbs/57647_t.png)
Intestinal Stem Cell Isolation and Culture in a Porcine Model of Segmental Small Intestinal Ischemia
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Intestinal ischemia remains a major cause of morbidity and mortality in human and veterinary patients. Many disease processes result in intestinal…
![The Organoid Reconstitution Assay (ORA) for the Functional Analysis of Intestinal Stem and Niche Cells](https://cloudfront.jove.com/files/thumbs/56329_t.png)
The intestinal epithelium is characterized by an extremely rapid turnover rate. In mammals, the entire epithelial lining is renewed within 4 - 5…