Chapter 10
Cell Cycle and Division
![What is the Cell Cycle?](https://cloudfront.jove.com/files/media/science-education/science-education-thumbs/10757.jpg)
The cell cycle refers to the sequence of events occurring throughout a typical cell’s life. In eukaryotic cells, the somatic cell cycle has two…
![Genomic DNA in Prokaryotes](https://cloudfront.jove.com/files/media/science-education/science-education-thumbs/10758.jpg)
The genome of most prokaryotic organisms consists of double-stranded DNA organized into one circular chromosome in a region of cytoplasm called the…
![Genomic DNA in Eukaryotes](https://cloudfront.jove.com/files/media/science-education/science-education-thumbs/10760.jpg)
Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside…
![Interphase](https://cloudfront.jove.com/files/media/science-education/science-education-thumbs/10761.jpg)
The cell cycle occurs over approximately 24 hours (in a typical human cell) and in two distinct stages: interphase, which includes three phases of…
![Positive Regulator Molecules](https://cloudfront.jove.com/files/media/science-education/science-education-thumbs/10763.jpg)
To consistently produce healthy cells, the cell cycle—the process that generates daughter cells—must be precisely regulated.
Internal…
![Negative Regulator Molecules](https://cloudfront.jove.com/files/media/science-education/science-education-thumbs/10764.jpg)
Positive regulators allow a cell to advance through cell cycle checkpoints. Negative regulators have an equally important role as they terminate a…
![Assessing Cell Cycle Progression of Neural Stem and Progenitor Cells in the Mouse Developing Brain after Genotoxic Stress](https://cloudfront.jove.com/files/thumbs/51209_t.png)
Neurons of the cerebral cortex are generated during brain development from different types of neural stem and progenitor cells (NSPC), which form a…
![Temporal Tracking of Cell Cycle Progression Using Flow Cytometry without the Need for Synchronization](https://cloudfront.jove.com/files/thumbs/52840_t.png)
This protocol describes a method to permit the tracking of cells through the cell cycle without requiring the cells to be synchronized. Achieving…