Fonte: Rachel Liu, BAO, MBBCh, Medicina d’urgenza, Yale School of Medicine, New Haven, Connecticut, USA
Il cuore si trova all’interno del pericardio, un sacco fibroso relativamente anelastico. Il pericardio ha una certa conformità ad allungarsi quando il fluido viene lentamente introdotto nello spazio pericardico. Tuttavia, il rapido accumulo travolge la capacità pericardica di ospitare liquidi extra. Una volta raggiunto un volume critico, la pressione intrapericardica aumenta drasticamente, comprimendo il ventricolo destro e infine ostacolando il volume che entra nel ventricolo sinistro. Quando queste camere non possono riempire la diastole, il volume dell’ictus e la gittata cardiaca diminuiscono, portando al tamponamento cardiaco, una compressione pericolosa per la vita delle camere cardiache da un versamento pericardico. A meno che la pressione non sia alleviata dall’aspirazione del liquido pericardico (pericardiocentesi), l’arresto cardiaco è imminente.
Il tamponamento cardiaco è un’emergenza critica che può portare alta morbilità e mortalità. I pazienti possono presentarsi in extremis, senza molto tempo per fare la diagnosi ed eseguire trattamenti salvavita. Le cause di questa condizione sono suddivise in categorie traumatiche e non traumatiche, con diversi algoritmi di trattamento. Le coltellate e le ferite da arma da fuoco sono la causa principale del tamponamento traumatico, ma possono verificarsi da traumi contundenti associati a fratture sternali o costali e taglio dei vasi da lesioni da rapida decelerazione. Le cause non traumatiche includono la rottura della base aortica dalla dissezione aortica ascendente, la rottura miocardica del ventricolo a seguito di infarto miocardico, sanguinamento spontaneo da farmaci trombolitici o anticoagulanti e versamenti creati da infezione o cancro.
I versamenti cronici a crescita lenta di solito non sono pericolosi per la vita, anche quelli di grandi dimensioni. Il pericardio si è gradualmente allungato per incorporare litri di liquido in alcuni casi. Questi possono essere trattati con pericardiocentesi elettiva sotto guida fluoroscopica o una finestra pericardica. Tuttavia, la transizione alla fisiologia del tamponamento con un paziente in extremis richiede una pericardiocentesi urgente, anche con una piccola quantità di liquido. Tamponade presenta una sfida da diagnosticare, poiché i suoi sintomi e risultati fisici sono spesso aspecifici, comuni a un certo numero di malattie. Un elettrocardiogramma (ECG o ECG) può mostrare alternanze elettriche e una radiografia del torace può mostrare una silhouette cardiaca “bottiglia d’acqua” ingrandita.
Tamponade should always rank highly in the diagnoses for undifferentiated shock, particularly in patients with prior cardiac disease, suspected aortic dissection, a history of malignancy, or anticoagulant use. Traumatic tamponade must be considered in both penetrating and blunt trauma scenarios, with temporizing pericardiocentesis performed in deteriorating patients while setting up for thoracotomy. High suspicion, clinical vigilance, understanding of tamponade physiology, and prompt action will help to avoid the deadly effects of this process.
In this modern age when imaging guidance is more prevalent, complications from deep or inappropriate needle insertion may be prevented. Patients requiring emergent pericardiocentesis often cannot sustain the time required to obtain fluoroscopy-guided or computed tomography (CT)-guided pericardiocentesis. However, bedside ultrasound is immediately available in many emergency departments and is a necessary adjunct to performing procedure. Needle entry into pericardial fluid can be viewed in real time, as well as real time aspiration. Placement in the appropriate location can be rapidly confirmed using agitated saline. Absence of pneumothorax or hemothorax can be rapidly assessed. Real time viewing also allows a better approach plan, providing more operator comfort in performing apical or parasternal approaches and thus improving success.
Pericardiocentesis has some complications that may become major. These include cardiac puncture or coronary vessel laceration, liver or stomach laceration, pneumothorax, hemothorax, pneumoperitoneum, pneumopericardium, suppurative pericarditis, and pulmonary edema due to sudden venous return to the left ventricle. Serious dysrhythmias are not common and may be vagal mediated. This may be prevented by giving atropine prior to the procedure. Failure of pericardiocentesis to yield fluid may be considered a complication, and is much more common in the blind approach.
Pericardiocentesis – the aspiration of fluid from the space between the heart and pericardium – is a potentially lifesaving procedure performed to relieve cardiac tamponade.
Cardiac tamponade occurs when fluid collects rapidly in the pericardial space, causing a dramatic increase in pressure inside this space. If untreated, the fluid accumulation will lead to cardiac arrest.
This video will review the etiology and diagnosis of cardiac tamponade, demonstrate the technique of pericardiocentesis using EKG guidance, and discuss the possible complications of the procedure.
The pericardium is a relatively inelastic fibrous sac, which surrounds the heart. If fluid accumulates slowly in the space between the pericardium and the heart – such as due to infection or cancer – the sac can stretch to accommodate it. However, a rapid accumulation of fluid in the pericardial space causes compression of the ventricles, which leads to decreased cardiac filling, diminished stroke volume, reduced cardiac output, and ultimately, cardiac arrest.
The reason behind cardiac tamponade could be non-traumatic, such as malignancy, myocardial infarction, or bleeding due to an anticoagulant medication. Or the cause could be traumatic like stabbings, or sternal or rib fractures.
Cardiac tamponade can be difficult to diagnose, as many of the findings are non-specific. Signs on physical exam include: diaphoresis, agitation, distended neck veins, an inability to lie flat, tachypnea, inability to speak full sentences and cyanosis. The patient may also be tachycardic, and upon auscultation of the chest wall, there will be muffled heart sounds. Also, the point of maximal impulse felt by palpation might be displaced. The patient may also be hypotensive and have a narrow pulse pressure. Or they may present with pulsus paradoxus, which is a decrease of the systolic blood pressure by more than 10 mm Hg during inspiration.
The EKG may demonstrate electrical alternans, which is an inconsistency in the height of the QRS complex. Also a chest X-ray may show an enlarged – or “water bottle” cardiac silhouette. A bedside echocardiography, if available, will demonstrate fluid in the pericardial space compressing the right ventricular wall during diastole.
Now that we have discussed the etiology and diagnoses for cardiac tamponade, lets review the protocol for pericardiocentesis under EKG guidance. Note that this can be performed blind or under ultrasound guidance as well.
Start by gathering the necessary equipment onto a sterile tray. This includes: a 60 cc syringe, a 18-gauge spinal needle, 1% Lidocaine, an alligator clip cable, a guidewire, a dilator, an 8 French pigtail catheter, an EKG machine, and suture, gauze and tape. Before starting the procedure on an obtunded patient, they should be stabilized with IV fluid boluses and may need vasopressors to support the blood pressure. Although intubation may be necessary, be aware that positive pressure in the thorax might place even more strain on the heart wall.
To begin the procedure, position the patient with their chest elevated to a 45° angle and ensure that the cardiac monitor is attached. If not intubated, administer oxygen via nasal cannula or a non-rebreather mask and give IV fluids. This procedure is most commonly performed via the sub-xiphoid approach. Therefore, start by cleansing the subxiphoid and epigastric region with betadine and place sterile drapes around the area. Note that the insertion site is 1 cm inferior to the xiphoid and the needle will be initially aimed toward the left shoulder. Anesthetize the skin and subcutaneous tissue along this path using 1% Lidocaine. Then, connect the spinal needle to the 60 cc syringe. Also, attach a precordial EKG lead located on the patient’s chest to the hub of the spinal needle using the alligator clip cable and start recording a rhythm strip from this lead.
Insert the spinal needle 1 cm below the xiphoid process and advance the needle slowly, aiming toward the left shoulder. Hold it at a 30° angle to the skin to avoid injuring the structures behind the heart. The depth of insertion depends on the individual’s habitus. Aspirate continually while the needle is being advanced and monitor the EKG strip. If there is no fluid return, withdraw the needle and re-direct it at a higher angle to the skin. If there is still no fluid, withdraw the needle and reinsert it at the same angle, aiming slightly more towards the mid-line. Continue to redirect the needle until fluid is aspirated. This might even require aiming the needle towards the right shoulder.
Once fluid enters the syringe, do not advance the needle any further. Note that the patient might experience sharp chest pain when the pericardium is pierced. If the tip of the needle touches the epicardium, the EKG will show an injury pattern that looks like a wide-complex PVC with ST elevation. If this occurs, withdraw the needle to prevent laceration of the myocardium. If the patient is in extremis, aspirate as much fluid at this point as possible, as this may result in rapid clinical improvement. Then, stabilize the needle to prevent it from penetrating further and remove the syringe from the needle.
The next step is to thread the guidewire through the spinal needle into the pericardial space, and remove the needle. Pass the dilator over the wire to dilate the subcutaneous tissue and then remove the dilator, leaving the guidewire in place. Next, pass the pigtail catheter over the guidewire and remove the guidewire. Now aspirate the fluid through the catheter and at the end place a stopcock on the catheter to allow for future aspiration of fluid. Laslty, cover the entrance site with gauze and tape and suture the free end of the catheter to the skin. Obtain a chest x-ray to rule out pneumothorax or pneumopericardium.
The potential risks of pericardiocentesis include: cardiac puncture, coronary vessel laceration, liver or stomach laceration, pneumothorax, hemothorax, pneumoperitoneum, pneumopericardium, suppurative pericarditis, and pulmonary edema. Serious dysrhythmias can also occur, but because these may be vagally mediated, pretreating with Atropine may prevent them.
“Cardiac tamponade is a life-threatening condition, which should always be considered in patients with undifferentiated shock, particularly if there is a history of malignancy or anticoagulant use, cardiac disease or suspected aortic dissection. If not treated using pericardiocentesis, this condition can lead rapidly to the patient’s demise.”
You have just watched JoVE’s video on pericardiocentesis for the treatment of life-threatening cardiac tamponade. You should now have a better understanding of the pathophysiology, diagnosis and emergency treatment of this condition. As always, thanks for watching!
