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1Centre for Infectious Diseases and Microbiology-Public Health,Westmead Hospital, 2Centre for Infectious Diseases and Microbiology Laboratory Services,ICPMR, 3Marie Bashir Institute for Infectious Diseases and Biosecurity,The University of Sydney, 4Department of Microbiology and Infectious Diseases, Canberra Hospital and Health Services,Australian National University Medical School, 5Infection Management Services,Australian National University Medical School, 6Department of Microbiology and Infectious Diseases,St. Vincent’s Hospital, 7Department of Infectious Diseases,Peter MacCallum Cancer Centre
Chapters
- 00:05Title
- 01:11Tagmentation and PCR Amplification
- 03:35PCR Cleanup
- 05:15Library Normalization
- 07:19Results: Susceptibility Profiles of Candida glabrata Isolates Correlates with Presence or Absence of Specific Gene Mutations
- 08:11Conclusion
इस अध्ययन के Candida glabrataमें रोधी दवा प्रतिरोध को प्रदान जीन में उत्परिवर्तनों के विश्लेषण के लिए पूरे जीनोम अनुक्रमण लागू किया । C. glabrata echinocandins, azoles और 5-flucytosine के लिए प्रतिरोधी अलग, पद्धति को वर्णन करने के लिए अनुक्रम थे । अलग की संवेदनशीलता प्रोफाइल की उपस्थिति या जीन में विशिष्ट उत्परिवर्तन पैटर्न के अभाव के साथ संबंधित ।
