A subscription to JoVE is required to view this content. Sign in or start your free trial.
Chapters
- 00:00Title
- 01:09Introduction
- 01:43Transection of the Peripheral Nerve (PN) and Removal of PN Segment
- 08:58Cervical Hemisection Injury and Transplantation of PN
- 13:20Treating the Area of Injury with Chondroitinase
- 17:07Representative Electrophysiological and Immunocytochemical Results
- 19:41Conclusion
Traumatic injury to the spinal cord disrupts communication with the brain. To restore lost connectivity we utilize a peripheral nerve graft to provide a substratum for regenerating fibers in combination with neurotrophic factors and matrix-modulating enzymes to remove inhibitory molecules to promote long distance growth.
