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Low-stress Route Learning Using the Lashley III Maze in Mice
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JoVE Journal Neuroscience
Low-stress Route Learning Using the Lashley III Maze in Mice

Low-stress Route Learning Using the Lashley III Maze in Mice

DOI:
10.3791/1786-v

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09:14 min

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May 22, 2010

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, ,
1Department of Chemistry,Pennsylvania State University, 2Center for Developmental and Health Genetics,Pennsylvania State University, 3Department of Veterinary and Biomedical Sciences,Pennsylvania State University, 4Huck Institute of the Life Sciences,Pennsylvania State University, 5California NanoSystems Institute,University of California, Los Angeles, 6Semel Institute of Neuroscience and Human Behavior,University of California, Los Angeles

Chapters

  • 00:00Title
  • 00:50Introduction
  • 01:08Part 1 – Preparing the Maze
  • 03:03Part 2 – Maze Testing
  • 06:32Representative Behavioral Results
  • 08:45Conclusion

Summary

Automatic Translation

Automatic Translation

The Lashley III maze is a route-learning task that does not rely on aversive stimuli or visual cues. It is thus a highly attractive option for evaluating learning and memory, especially in aging mice or otherwise where stress is a consideration.

Tags

Low-stressRoute LearningLashley III MazeMiceBehavior TestsLearning And MemoryVisual CuesAversive StimuliSensory ModalitiesAging AnimalsConfounding EffectsMaze NavigationLow Stress ConditionsDark PhaseFood/water DeprivationPseudo-home Cage

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