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Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity
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Neuroscience
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JoVE Journal Neuroscience
Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity

Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity

DOI:
10.3791/3439-v

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07:42 min

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April 26, 2012

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, ,
1Prince of Wales Clinical School,University of New South Wales , 2Neuroscience Research Australia,University of New South Wales , 3School of Medical Sciences,University of New South Wales

Chapters

  • 00:05Title
  • 01:32Patient and Axonal Excitability Preparation
  • 03:46Axonal Excitability Protocols
  • 05:43Patient Assessment: Analysis and Interpretation
  • 06:57Examples of Excitability Results
  • 07:22Conclusion

Summary

Automatic Translation

Automatic Translation

This abstract describes a novel method to assess the development of neurotoxicity in patients receiving chemotherapy treatment. While conventional assessment methods are limited in their ability to detect early changes in nerve function, nerve excitability techniques provide early identification of patients at risk of severe neurotoxicity and insight into pathophysiology.

Tags

Nerve Excitability AssessmentChemotherapy-induced NeurotoxicityPeripheral NeuropathyFine Motor SkillsWalking DifficultiesFunctional ImpairmentDose ReductionTreatment CessationNeuropathic SymptomsNerve DamageNeuroprotective AgentsAssessment MethodsClinician-based Grading ScalesNerve Conduction Studies

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