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调查在DSS诱导的鸡传染性法氏囊病模型的肠道炎症
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Investigating Intestinal Inflammation in DSS-induced Model of IBD
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调查在DSS诱导的鸡传染性法氏囊病模型的肠道炎症

DOI:
10.3791/3678-v

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08:43 min

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February 01, 2012

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, , ,
1Farncombe Family Digestive Health Research Institute, Department of Pathology and Molecular Medicine,McMaster University

Chapters

  • 00:05Title
  • 01:33Collection of Colonic Tissue Samples and Assessment of Colitis Severity
  • 03:58Sample Preparation for Myeloperoxidase (MPO) Assay
  • 05:09Quantification of Inflammatory Markers
  • 06:01Evaluating the Severity of Acute Colitis in DSS-treated Animals
  • 08:23Conclusion

Summary

Automatic Translation

Automatic Translation

发炎性肠道疾病的实验模型使我们能够研究与发病机制相关的复杂的先天免疫和适应性免疫反应。使用组织学评分，量化促炎性细胞因子和髓过氧化物酶活性，就可以开始评估在炎症性肠病看到这些答复。

Tags

Intestinal InflammationDSS-induced ModelIBDUlcerative ColitisCrohn’s DiseasePathogenesisGeneticEnvironmental ComponentsAnimal ModelsColonic InflammationDextran Sulphate SodiumColitis-inducing ChemicalsAcute ColitisChronic ColitisWeight LossLoose StoolDiarrheaRectal BleedingHistological AnalysisPro-inflammatory Cytokines

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