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Chapters
- 00:05Title
- 01:59Whole Blood Preparations
- 03:05Preparing the Plasma for Biochemical Analysis
- 04:26Preparing the Red Blood Cells for Biochemical Analysis
- 05:18Tissue Extraction and Preparation
- 06:02Aortic Ring Isolations
- 08:10Analyzing Endothelial Function
- 09:25Dose Response to Acetylcholine
- 10:11Conclusion
The endogenous production of nitric oxide (NO) regulates a wide variety of biological functions. It is becoming increasingly clear that disruption or dysregulation of NO based signaling is involved in many human diseases. Methods to quantify relevant NO metabolites may provide novel diagnostic or prognostic biomarkers for human disease.
Tags
Analytical TechniquesAssayingNitric Oxide BioactivityDetectionQuantificationSignaling MoleculesBlood Pressure RegulationImmune Response RegulationNeural Communication RegulationAccurate DetectionQuantification In Biological MatricesPhysiological Half LifeAlternative StrategiesDetection Of Reaction ProductsNO MetabolitesBiological CompartmentsIn Vivo NO ProductionBioavailabilityMetabolismWhole Body NO StatusDiagnostic UtilityPrognostic UtilityNO Biomarkers
