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Klinisk testing og Spinal Cord fjerning i en mus modell for Amyotrofisk lateral sklerose (ALS)
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JoVE Journal Medicine
Clinical Testing and Spinal Cord Removal in a Mouse Model for Amyotrophic Lateral Sclerosis (ALS)

Klinisk testing og Spinal Cord fjerning i en mus modell for Amyotrofisk lateral sklerose (ALS)

DOI:
10.3791/3936-v

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12:35 min

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March 17, 2012

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, , , , ,
1Dept. of Neurology,University Medicine Göttingen, 2DFG Research Center for the Molecular Physiology of the Brain (CMPB),Göttingen, Germany

Chapters

  • 00:02Title
  • 01:07Clinical Testing of the SOD G93A Mouse Model of ALS
  • 02:03Hanging Wire Test
  • 03:05Rotarod Test
  • 04:30Spinal Cord Preparation
  • 10:55Spinal Cord Immunohistochemistry
  • 11:41Conclusions

Summary

Automatic Translation

Automatic Translation

En mus modell for amyotrofisk lateral sklerose (ALS) er undersøkt klinisk og behaviorally. Som en forutsetning for en ledsagende immunhistokjemi analyse utarbeidelse av ryggmargen er avbildet i detalj.

Tags

Clinical TestingSpinal Cord RemovalMouse ModelAmyotrophic Lateral SclerosisALSNeurodegenerative DisorderMotoneuronsFamilial MutationsSOD GeneSOD1 (G93A) MutationOverall SurvivalClinical CourseMotor FunctionBehavioural Motor TestsQuantitative Scoring SystemsImmunohistochemical ExaminationSpinal Cord PreparationDorsal Laminectomy MethodHistological FindingsTherapeutic OptionsHuman Clinical Trials

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