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Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis
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Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis

Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis

DOI:
10.3791/51056-v

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08:16 min

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March 04, 2014

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,
1Department of Neurology,Westmead Hospital, 2Sydney Medical School,University of Sydney, Australia

Chapters

  • 00:05Title
  • 01:35Patient Preparation and Clinical Assessment
  • 02:49Neurophysiological Assessment
  • 05:31Analysis and Interpretation
  • 06:50Results: Split-hand Index Reduced in Amyotrophic Lateral Sclerosis Patients
  • 07:43Conclusion

Summary

Automatic Translation

Automatic Translation

Dissociated atrophy of intrinsic hand muscles, termed the split hand, appears to be a specific feature of amyotrophic lateral sclerosis (ALS). Consequently, a novel neurodiagnostic test, termed the split hand index, was developed to quantify the clinical phenomenon of the split hand, which differentiated ALS from mimic disorders.

Tags

Amyotrophic Lateral SclerosisALSSplit Hand PhenomenonSplit Hand IndexCompound Muscle Action PotentialCMAPAbductor Pollicis BrevisFirst Dorsal InterosseousAbductor Digiti MinimiNeuromuscular DisordersDiagnostic Biomarker

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