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Chapters
- 00:05Title
- 01:14Operative Procedure and Postoperative Care
- 02:50Functional Studies Twenty-Four Hours Post Intestinal Manipulation
- 04:32Colon Transit Time
- 05:03Histochemical Analysis and Organ Culture of Muscularis Externa
- 07:25Representative Post Operative Ileus Results
- 09:15Conclusion
Postoperativ ileus (POI) er en komplikation af abdominal kirurgi fører til øget sygelighed og en forlænget sygehusophold. Fordi profylaktiske eller terapeutiske strategier mangler intensiveret forskning er nødvendig. Derfor har vi etableret et standardiseret og muligt musemodel til at undersøge patofysiologien af POI og til at studere potentielle terapeutiske muligheder.
Tags
Functional AssessmentIntestinal MotilityGut Wall InflammationRodentsStandardized ModelIntestinal ManipulationGastrointestinal TractHuman DiseasesAnimal Research ModelsCellular And MolecularIntestinal PathologyTunica MucosaMuscularis ExternaImmunocompetent OrganResident ImmunocytesInflammation Of The Bowel WallPostoperative IleusAbdominal SurgeryProinflammatory MediatorsIL-6IL-1βNitric Oxide (NO)Immunocytes ExtravasatePolymorphonuclear Neutrophils (PMN)MonocytesIntestinal ParalysisIncreased Risk Of AspirationBacterial TranslocationInfectious ComplicationsSepsisMulti Organ Failure
