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Multi-analyte Biochip (MAB) Based on All-solid-state Ion-selective Electrodes (ASSISE) for Physiological Research
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1Department of Agricultural and Biological Engineering, Birck-Bindley Physiological Sensing Facility,Purdue University, 2NASA Ames Research Center, 3Department of Chemistry,Pennsylvania State University Hazleton, 4Cooley LLP, 5NASA Life and Physical Sciences, Human Exploration and Operations Mission Directorate,NASA Headquarters
Chapters
- 00:05Title
- 01:25Electropolymerization of PEDOT-based Conductive Polymer
- 03:20Application of Ion-selective Membrane
- 03:53Calibration of PEDOT-PSS Conductive Polymer Conjugate with pH and Carbonate (CO32-) Ion-selective Membrane
- 05:46Results: Physiological Research Applications
- 07:42Conclusion
All-solid-state ion-selective electrodes (ASSISEs) constructed from a conductive polymer (CP) transducer provide several months of functional lifetime in liquid media. Here, we describe the fabrication and calibration process of ASSISEs in a lab-on-a-chip format. The ASSISE is demonstrated to have maintained a near-Nernstian slope profile after prolonged storage in complex biological media.
