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Behavior
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帕金森氏症小鼠模型的感觉功能评估
JoVE Journal
Behavior
This content is Free Access.
JoVE Journal
Behavior
Assessment of Sensorimotor Function in Mouse Models of Parkinson’s Disease
Please note that all translations are automatically generated.
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帕金森氏症小鼠模型的感觉功能评估
DOI:
10.3791/50303-v
•
10:32 min
•
June 17, 2013
•
Sheila M. Fleming
2
,
Osunde R. Ekhator
2
,
Valentins Ghisays
1
Department of Psychology
,
University of Cincinnati
,
2
Department of Neurology
,
University of Cincinnati
Chapters
00:05
Title
01:23
Challenging Beam Traversal Procedure
05:22
Spontaneous Activity in the Cylinder Procedure
07:26
Adhesive Removal Test
09:00
Results: Assessment of Sensorimotor Function in Mice
10:04
Conclusion
Summary
Automatic Translation
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Automatic Translation
在帕金森氏病和运动障碍一般，敏感和可靠的行为分析是必不可少的，用于测试新的潜在疗法。在这里，我们描述了一个可管理的电池感觉敏感不同程度的损伤，黑质纹状体系统，并用于临床前研究的老鼠试验。
Tags
Keywords: Sensorimotor Function
Mouse Models
Parkinson’s Disease
Behavioral Outcome Measures
Preclinical Trials
Nigrostriatal Dysfunction
Sensorimotor Tests
Genetic Mouse Models
Disease-modifying Therapies
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