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通过胎盘的外来物质和纳米材料的运输率测定<em>体外</em>人胎盘灌注型号

JoVE Journal
Bioengineering

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JoVE Journal Bioengineering

Determination of the Transport Rate of Xenobiotics and Nanomaterials Across the Placenta using the ex vivo Human Placental Perfusion Model

Please note that all translations are automatically generated. Click here for the English version.

通过胎盘的外来物质和纳米材料的运输率测定<em>体外</em>人胎盘灌注型号

DOI:

10.3791/50401-v

•

08:08 min

•

June 18, 2013

•

Stefanie Grafmüller^2,3, Pius Manser, Harald F. Krug, Peter Wick, Ursula von Mandach

¹Department of Obstetrics, Perinatal Pharmacology,University Hospital Zurich, ²Laboratory for Materials – Biology Interactions,EMPA Swiss Federal Laboratories for Materials Testing and Research, ³Graduate School for Cellular and Biomedical Sciences,University of Bern

Chapters

00:05Title
01:36Preparing the Perfusion System
02:38Cannulating the Placenta
05:01Executing the Pre- and Experimental Phase of Perfusion
06:21Results: Determination of the Transport Rate of Xenobiotics and Nanomaterials Across the Placenta Using the Ex vivo Human Placental Perfusion Model
07:44Conclusion

Summary

Automatic Translation

该<em>体外</em>双循环人胎盘灌注模型可用于研究的整个人的胎盘转移的外源物和纳米颗粒。在这个视频协议中，我们描述了一个胎盘灌注成功执行所需的设备和技术。

Tags

Placental Perfusion Xenobiotics Nanomaterials Placental Barrier Ex Vivo Model Fetal Exposure Nanoparticles Polystyrene Particles Transport Rate Human Placenta

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