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JoVE Journal
Immunology and Infection

This content is Open Access.

An Experimental Model to Study Tuberculosis-Malaria Coinfection upon Natural Transmission of Mycobacterium tuberculosis and Plasmodium berghei
 

An Experimental Model to Study Tuberculosis-Malaria Coinfection upon Natural Transmission of Mycobacterium tuberculosis and Plasmodium berghei

Article DOI: 10.3791/50829-v 09:02 min February 17th, 2014
February 17th, 2014

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Summary

Tuberculosis and malaria are two of the most prevalent infections in humans and major causes of morbidity and mortality in impoverished populations in the tropics. We established an experimental model system to study outcome of malaria-tuberculosis coinfection in mice after challenge with both pathogens via their natural route of infection.

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Keywords: Tuberculosis Malaria Coinfection Mycobacterium Tuberculosis Plasmodium Berghei Natural Transmission Experimental Mouse Model Immune Response Pathogenesis Disease Outcome Sub-Saharan Africa
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