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A Murine Model of Cervical Spinal Cord Injury to Study Post-lesional Respiratory Neuroplasticity
 

A Murine Model of Cervical Spinal Cord Injury to Study Post-lesional Respiratory Neuroplasticity

Article DOI: 10.3791/51235-v 09:09 min May 28th, 2014
May 28th, 2014

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Summary

Respiratory failure is the leading cause of death following a cervical spinal cord injury. Having a reproducible, quantifiable, and reliable pre-clinical animal model of respiratory failure induced by a partial cervical injury will help to understand the subsequent respiratory and non-respiratory neuroplasticity and allow testing putative repair strategies.

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Keywords: Murine Model Cervical Spinal Cord Injury Respiratory Neuroplasticity Pre-clinical Model C2 Level Injury Diaphragm Paralysis Phrenic Nerve Respiratory Function Respiratory Neuroplasticity Therapeutic Strategies Respiratory Failure
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