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DNBS / TNBS Colitis modeller: giver indsigt i inflammatorisk tarmsygdom og Effekter af kosten fedt
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DNBS/TNBS Colitis Models: Providing Insights Into Inflammatory Bowel Disease and Effects of Dietary Fat

DNBS / TNBS Colitis modeller: giver indsigt i inflammatorisk tarmsygdom og Effekter af kosten fedt

DOI:
10.3791/51297-v

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09:04 min

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February 27, 2014

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, , , , , ,
1Division of Gastroenterology,BC Children’s Hospital

Chapters

  • 00:05Title
  • 01:24Intra Rectal Dinitrobenzene Sulfonic Acid (DNBS) Administration
  • 02:52Collecting Tissues and Assessing Histological Damage in DNBS Challenged Mice
  • 04:27Myeloperoxidase (MPO) Assay of DNBS Challenged Intestinal Tissue
  • 05:25Results: Representative Effects of Dietary Oils on DNBS Colitis Severity of DNBS Challenged Intestinal Tissue
  • 08:18Conclusion

Summary

Automatic Translation

Automatic Translation

DNBS / TNBS induceret colitis tilbyder et alternativ og billig metode til at studere Patobiologi af inflammatorisk tarmsygdom. Protokollen diskuteret i dette dokument skitserer den vellykkede anvendelse af DNBS at fremkalde colitis hos mus og rotter, og tillader en at grundigt studere værtsmedierede tarm reaktioner.

Tags

Keywords: DNBSTNBSColitisInflammatory Bowel DiseaseDietary FatN-3 Fatty AcidsN-6 Fatty AcidsSafflower OilCanola OilFish OilWeight LossMucosal InflammationMyeloperoxidase

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