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Controlling Parkinson’s Disease With Adaptive Deep Brain Stimulation
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JoVE Journal Medicine
Controlling Parkinson’s Disease With Adaptive Deep Brain Stimulation

Controlling Parkinson’s Disease With Adaptive Deep Brain Stimulation

DOI:
10.3791/51403-v

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11:12 min

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July 16, 2014

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, , , , , , ,
1Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital,University of Oxford, 2Sobell Department of Motor Neuroscience & Movement Disorders, Unit of Functional Neurosurgery,UCL Institute of Neurology

Chapters

  • 00:05Title
  • 02:17Consent and Biomarker Identification
  • 04:25Connection of Patient to aDBS Setup
  • 05:33Testing of Conventional Continuous Stimulation
  • 06:22Testing of Threshold with On / Off Switching and Trigger Setting
  • 08:12Testing of Patient Across Different Stimulation Conditions
  • 09:38Results: Clinical Improvements with aDBS
  • 10:36Conclusion

Summary

Automatic Translation

Automatic Translation

Adaptive deep brain stimulation (aDBS) is effective for Parkinson’s disease, improving symptoms and reducing power consumption compared to conventional deep brain stimulation (cDBS). In aDBS we track a local field potential biomarker (beta oscillatory amplitude) in real time and use this to control the timing of stimulation.

Tags

Parkinson’s DiseaseAdaptive Deep Brain StimulationADBSSubthalamic NucleusBeta AmplitudeReal-time OptimizationMotor FunctionUPDRSPower ConsumptionChronic Stimulation

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