Olfactory Assays for Mouse Models of Neurodegenerative Disease

Andrew M. Lehmkuhl; Emily R. Dirr; Sheila M. Fleming

doi:10.3791/51804

Journal

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Neuroscience

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嗅觉测定的神经退行性疾病的小鼠模型

JoVE Journal
Neuroscience

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JoVE Journal Neuroscience

Olfactory Assays for Mouse Models of Neurodegenerative Disease

Please note that all translations are automatically generated. Click here for the English version.

嗅觉测定的神经退行性疾病的小鼠模型

DOI:

10.3791/51804-v

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07:27 min

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August 25, 2014

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Andrew M. Lehmkuhl, Emily R. Dirr³, Sheila M. Fleming²

¹Department of Psychology,University of Cincinnati, ²Department of Neurology,University of Cincinnati, ³Department of Neuroscience, Cell Biology, and Physiology,Wright State University

Chapters

00:05Title
01:21Buried Pellet Test
03:15Block Test
05:26Habituation/Dishabituation
06:18Results: Olfactory Assays for Mouse Models of Neurodegenerative Disease
06:52Conclusion

Summary

Automatic Translation

Impairment in olfactory function is a common feature in many neurodegenerative disorders including Parkinson, Alzheimer, and Huntington diseases. In the present article, we describe a set of tests for assessing olfaction discrimination and detection in mice that can be used to measure olfactory abilities in mouse models of neurodegenerative diseases.

嗅觉测定的神经退行性疾病的小鼠模型

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