A subscription to JoVE is required to view this content. Sign in or start your free trial.
Chapters
- 00:05Title
- 01:12Tracheal Intubation Cannula Preparation
- 02:12Intubation
- 04:07Thoracotomy and Thymectomy
- 07:12Results: Attrition of Peripheral Blood Naïve T Cells Post-thymectomy
- 08:07Conclusion
Rodent thymectomy is a valuable technique in immunological research. Here, a protocol for complete thymectomy in adult rats using a mini-sternotomy along with non-invasive intubation and positive pressure ventilation to minimize perioperative morbidity and mortality is described.
