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Chapters
- 00:05Title
- 01:18Setting up the Gas Chromotagraph
- 02:24Measuring the Diffusion Factor for Carbon Monoxide (DFCO)
- 04:46Results: Changes in DFCO in Different Pathologies
- 06:39Conclusion
We describe a means to quickly and simply measure the lung diffusing capacity in mice and show that it is sufficiently sensitive to phenotype changes in multiple common lung pathologies. This metric thus brings direct translational relevance to the mouse models, since diffusing capacity is also easily measured in humans.
