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Мышь кожу плода Модель шрамов заживления ран
JoVE Journal
Medicine
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JoVE Journal Medicine
A Mouse Fetal Skin Model of Scarless Wound Repair
DOI:

09:20 min

January 16, 2015

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Chapters

  • 00:05Title
  • 01:07Timed Pregnancies – Superovulation Technique
  • 02:49Murine Fetal Surgery (Dorsal Wounding) on E16.5 and E18.5 Embryos
  • 06:05Post-operative Care and Fetus Harvesting
  • 07:40Results: E16.5 Versus E18.5 Wound Healing
  • 09:00Conclusion

Summary

Automatic Translation

During mammalian development, early gestational skin wounds heal without a scar. Here we detail a reliable and reproducible model of fetal scarless wound healing in the cutaneous dorsum of E16.5 (scarless) and E18.5 (scarring) mouse embryos.

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