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Journal / Neuroscience / Real-time Electrophysiology: Using Closed-loop…
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JoVE Journal Neuroscience
Real-time Electrophysiology
 

Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond

Article DOI: 10.3791/52320-v • 08:08 min • June 24th, 2015
June 24th, 2015 •
1, 1, 1
1Department of Biomedical Sciences, University of Antwerp

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Summary
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Closed-loop protocols are becoming increasingly widespread in modern day electrophysiology. We present a simple, versatile and inexpensive way to perform complex electrophysiological protocols in cortical pyramidal neurons in vitro, using a desktop computer and a digital acquisition board.

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Keywords: Real-time Electrophysiology Closed-loop Protocols Neuronal Dynamics Virtual Reality Optogenetics Neuronal Excitability Reliability Patch Clamp Somatosensory Cortex LCG Software
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