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An Assay for Measuring the Effects of Ethanol on the Locomotion Speed of Caenorhabditis elegans
 

An Assay for Measuring the Effects of Ethanol on the Locomotion Speed of Caenorhabditis elegans

Article DOI: 10.3791/52681-v • 10:35 min • April 9th, 2015
April 9th, 2015 •
1,2, 1,2, 1, 1,2
1Department of Pharmacology and Toxicology, Virginia Commonwealth University, 2VCU Alcohol Research Center, Virginia Commonwealth University

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Summary
Automatic Translation

C. elegans is a useful model for studying the effects of ethanol on behavior. We present a behavioral assay that quantifies the effects of ethanol on the locomotion speed of crawling worms; both initial sensitivity and the development of acute functional tolerance to ethanol can be measured with this assay.

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Keywords: Caenorhabditis Elegans Ethanol Locomotion Assay Behavioral Plasticity Initial Sensitivity Acute Functional Tolerance
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