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Chapters
- 00:05Title
- 01:27Fly Collection and Climbing Assay
- 03:57Analysis of Fly Performance
- 04:54Results: Climbing Deficits in a Drosophila Model of Neurodegenerative Disorders
- 06:01Conclusion
We present an optimized inexpensive and reliable negative geotaxis assay in Drosophila melanogaster as a model for neurodegenerative disorders. Being more sensitive to mild locomotor defects, this assay will help screen for potential genetic interactions and drug targets.
