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Establishment and Characterization of UTI and CAUTI in a Mouse Model
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Establishment and Characterization of UTI and CAUTI in a Mouse Model

Establishment and Characterization of UTI and CAUTI in a Mouse Model

DOI:
10.3791/52892-v

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08:40 min

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June 23, 2015

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, , , ,
1Department of Molecular Microbiology and Center for Women’s Infectious Disease Research,Washington University School of Medicine

Chapters

  • 00:05Title
  • 01:42UPEC UTI Protocol, Bacterial Inoculation
  • 03:04Urine Collection for Bacteriuria CFU Enumeration and the Catheter Associated Urinary Tract Infection Model Protocol
  • 05:10Determination of Bacterial Burden
  • 06:20Results: Urinary Tract Infection and Catheter Associated UTI Colonization
  • 08:00Conclusion

Summary

Automatic Translation

Automatic Translation

The ability to model urinary tract infections (UTI) is crucial in order to be able to understand bacterial pathogenesis and spawn the development of novel therapeutics. This work’s goal is to demonstrate mouse models of experimental UTI and catheter associated UTI that recapitulate and predict findings seen in humans.

Tags

Keywords: Urinary Tract InfectionUTICatheter-associated UTICAUTIUropathogenic Escherichia ColiUPECEnterococcus FaecalisMouse ModelPathogenesisVirulenceHost ResponseIntracellular Bacterial CommunityIBCFilamentationAntibiotic ResistanceRecurrenceTreatmentPrevention

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