Journal
/
/
Establishment of a Mouse Severe Acute Pancreatitis Model using Retrograde Injection of Sodium Taurocholate into the Biliopancreatic Duct
JoVE Journal
Medicine
Author Produced
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Medicine
Establishment of a Mouse Severe Acute Pancreatitis Model using Retrograde Injection of Sodium Taurocholate into the Biliopancreatic Duct
DOI:

07:10 min

April 01, 2022

, , , , ,

Chapters

  • 00:00Introduction
  • 00:40Preparation
  • 01:12Anesthesia and Pre-Operative Preparation
  • 02:08Surgical Procedure
  • 04:11Recovery and Post-Operative Management
  • 04:31Serological Testing and Histology Evaluation
  • 05:23Representative Results
  • 06:25Conclusion

Summary

Automatic Translation

A mouse model of severe acute pancreatitis is described herein. The procedure presented here is very rapid, simple, and accessible, thereby potentially allowing the study of the molecular mechanisms and different therapeutic interventions in acute pancreatitis in a convenient way.

Related Videos

Read Article