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汽车和海马依赖空间学习和记忆参考评估与中风阿尔茨海默氏病的转基因大鼠模型

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JoVE Journal Medicine

Motor and Hippocampal Dependent Spatial Learning and Reference Memory Assessment in a Transgenic Rat Model of Alzheimer’s Disease with Stroke

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汽车和海马依赖空间学习和记忆参考评估与中风阿尔茨海默氏病的转基因大鼠模型

DOI:

10.3791/53089-v

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09:45 min

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March 22, 2016

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Jennifer L. Au, Nina Weishaupt, Hayley J. Nell, Shawn N. Whitehead, David F. Cechetto

¹Anatomy and Cell Biology, Schulich School of Medicine and Dentistry,Western University

Chapters

00:05Title
01:03Cylinder Task for Gross Forelimb Motor Assessment
02:37Beam-walk Task for Gross Motor Assessment
04:27Morris Water Maze for Spatial Learning and Reference Memory
07:33Results: A Comorbid Rat Model of Alzheimer’s Disease and Stroke Demonstrates Locomotion and Reference Memory Deficits
09:11Conclusion

Summary

Automatic Translation

调查在一个新颖模型共同病态阿尔茨海默氏病（AD）和中风的条件，都描述了三种行为任务评估两个电动机控制和认知行为。这些任务包括梁行走任务，气缸任务和Morris水迷宫。

Tags

Motor Function Spatial Learning Reference Memory Alzheimer’s Disease Stroke Comorbid Model Behavioral Assessment Motor Deficit Cognitive Decline Dementia Preventative Compounds Cylinder Apparatus Video Tracking Four-limb Contacts

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