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Chapters
- 00:05Title
- 01:37Unpredictable Chronic Mild Stress Protocol
- 03:50Animal Monitoring and Grooming Scores
- 04:37Behavioral Testing: The Sucrose Splash and Tail Suspension Tests
- 05:15Results: Measures of Physiological Changes in Mice Due to Unpredictable Chronic Mild Stress
- 06:12Conclusion
The unpredictable chronic mild stress (UCMS) protocol is a validated method for studying behavioral and physiological changes associated with chronic stress and depressive symptoms. Eight weeks of imposition of the UCMS protocol induces behavioral changes and poor health outcomes in rodents of either gender.
