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Chapters
- 00:05Title
- 01:30Isolation of Mononuclear Cells
- 03:42Staining Mononuclear Cells with CD45-FITC Antibody
- 05:33Injection of Circulating Tumor Cells into Mice
- 06:30Results: Generation of Prostate Cancer PDX Models
- 07:36Conclusion
This manuscript details a method used to generate prostate cancer patient derived xenografts (PDXs) from circulating tumor cells (CTCs). The generation of PDX models from CTCs provides an alternative experimental model to study prostate cancer; the most commonly diagnosed tumor and a frequent cause of death from cancer in men.
