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布洛芬封装的输运性质环糊精Nanosponge凝胶：质子HR-MAS NMR光谱研究

JoVE Journal
Bioengineering

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JoVE Journal Bioengineering

Transport Properties of Ibuprofen Encapsulated in Cyclodextrin Nanosponge Hydrogels: A Proton HR-MAS NMR Spectroscopy Study

Please note that all translations are automatically generated. Click here for the English version.

布洛芬封装的输运性质环糊精Nanosponge凝胶：质子HR-MAS NMR光谱研究

DOI:

10.3791/53769-v

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10:10 min

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August 15, 2016

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Monica Ferro*¹, Franca Castiglione*¹, Carlo Punta, Lucio Melone², Walter Panzeri, Barbara Rossi, Francesco Trotta, Andrea Mele

¹Department of Chemistry, Materials and Chemical Engineering “G. Natta”,Politecnico di Milano, ²Università degli studi e-Campus, ³ICRM,CNR – Consiglio Nazionale delle Ricerche, ⁴Elettra Sincrotrone Trieste, ⁵Department of Chemistry,University of Torino

Chapters

00:05Title
01:19Synthesis of Cyclodextrin Nanosponge Polymers
03:36HR-MAS NMR Measurements
07:05Results: How to Detect Variations of the Transport Properties of the Drug Encapsulated in the Hydrogel in Relation to the Nanosponge Synthesis
08:50Conclusion

Summary

Automatic Translation

布洛芬包封在β环糊精纳米海绵聚合物网络的运动制度使用脉冲场梯度自旋回波（PGSE）NMR技术分析。合成，纯化，载药量，实施核磁共振脉冲序列和数据分析在几个观察时间制定出药物的均方位移的详细描述。

Tags

Keywords: Cyclodextrin Nanosponges Hydrogels Ibuprofen Transport Properties HR-MAS NMR Spectroscopy Drug Delivery Step-growth Polymerization EDTA Dianhydride

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