A subscription to JoVE is required to view this content. Sign in or start your free trial.
Chapters
- 00:05Title
- 01:13Surgical Preparations
- 03:02Iliac Artery Ballon Injury Surgery
- 05:21Post-operative Care
- 06:00Tissue Harvesting and Analysis of Plaque Composition
- 07:05Results
- 08:41Conclusion
Animal models of atherosclerosis are essential to understand the mechanism and to investigate newer approaches to prevent plaque development or rupture, a leading cause of death in the industrialized world. This protocol uses a combination of balloon injury and cholesterol rich diet to induce atherosclerotic plaques in rabbit iliac artery.
