JoVE Journal
Neuroscience
Neuroscience
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外周注射的α-突触核蛋白原纤维进入的Tg的腹膜或舌的(M83 +/-:GFAP -luc +/-)小鼠,表达人α-突触核蛋白与家族性A53T突变和萤火虫萤光素酶,可诱发神经病理学,包括神经炎症在他们的中枢神经系统。