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Magnetic and Thermal-sensitive Poly(N-isopropylacrylamide)-based Microgels for Magnetically Triggered Controlled Release
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
Magnetic and Thermal-sensitive Poly(N-isopropylacrylamide)-based Microgels for Magnetically Triggered Controlled Release
DOI:

08:39 min

July 04, 2017

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Chapters

  • 00:05Title
  • 01:08Synthesis of Organic-inorganic Hybrid Microgels
  • 04:15Synthesis and Testing of Curcumin-loaded PNIPAAm/Fe3O4-NH2 Microgels
  • 06:25Results: Magnetically-controlled Curcumin Release from Cur-PNIPAAm/Fe3O4-NH2 Microgels
  • 08:06Conclusion

Summary

Automatic Translation

This manuscript describes the preparation of magnetic and thermal-sensitive microgels via a temperature-induced emulsion without chemical reaction. These sensitive microgels were synthesized by mixing poly(N-isopropylacrylamide) (PNIPAAm), polyethylenimine (PEI) and Fe3O4-NH2 nanoparticles for the potential use in magnetically and thermally triggered drug-release.

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