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遗传工程小鼠模型的散发性结肠直肠癌

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Cancer Research

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JoVE Journal Cancer Research

A Genetically Engineered Mouse Model of Sporadic Colorectal Cancer

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遗传工程小鼠模型的散发性结肠直肠癌

DOI:

10.3791/55952-v

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06:01 min

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July 06, 2017

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Alexander M. Betzler, Susan Kochall, Linda Blickensdörfer, Sebastian A. Garcia, May-Linn Thepkaysone, Lahiri K. Nanduri, Michael H. Muders, Jürgen Weitz^4,5, Christoph Reissfelder, Sebastian Schölch^4,5

¹Department of Gastrointestinal, Thoracic and Vascular Surgery, Medizinische Fakultät Carl Gustav Carus,Technische Universität Dresden, ²Department of General, Gastrointestinal and Transplant Surgery,University of Heidelberg, ³Department of Pathology, Medizinische Fakultät Carl Gustav Carus,Technische Universität Dresden, ⁴German Cancer Consortium (DKTK), ⁵German Cancer Research Center (DKFZ)

Chapters

00:05Title
00:51Segmental Adeno-cre Virus Colon Infection
04:11Results: Representative Mouse Colorectal Tumors
05:16Conclusion

Summary

Automatic Translation

提出了通过节段性腺病毒感染建立结肠直肠癌基因工程小鼠模型的方法及其通过高分辨率结肠镜检查进行的监测。

Tags

Genetically Engineered Mouse Model Sporadic Colorectal Cancer Adeno-cre Infection Colon-localized Tumors Colon Segment Inflation Trypsin-EDTA Adenoviral Solution Colonoscopy

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