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流感血凝素特异抗体诱导的 Fc 介导效应函数的一种评估方法
JoVE Journal
Immunology and Infection
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JoVE Journal Immunology and Infection
A Method to Assess Fc-mediated Effector Functions Induced by Influenza Hemagglutinin Specific Antibodies
DOI:

04:47 min

February 23, 2018

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Chapters

  • 00:05Title
  • 00:42Influenza Virus Hemagglutinin Expression
  • 02:18Antibody-dependent Cell-mediated Cytotoxicity (ADCC) Analysis
  • 04:01Results: Representative ADCC Analysis
  • 04:24Conclusion

Summary

Automatic Translation

我们描述了一种方法来衡量 Fc 介导的效应函数的活化作用的抗体, 针对流感病毒血凝素。这种检测也可以适应评估单克隆抗体或多克隆血清靶向其他病毒表面糖蛋白, 以诱导 Fc 介导的免疫能力。

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