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Synthesis of Monocyte-targeting Peptide Amphiphile Micelles for Imaging of Atherosclerosis
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Bioengineering
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JoVE Journal Bioengineering
Synthesis of Monocyte-targeting Peptide Amphiphile Micelles for Imaging of Atherosclerosis

Synthesis of Monocyte-targeting Peptide Amphiphile Micelles for Imaging of Atherosclerosis

DOI:
10.3791/56625-v

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08:01 min

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November 17, 2017

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, ,
1Department of Biomedical Engineering,University of Southern California

Chapters

  • 00:05Title
  • 01:01Monocyte Chemoattractant-1 (MCP-1) Peptide Amphiphile Micelle (PAM) Preparation
  • 04:10MCP-1 PA Preparation and Assembly
  • 05:44Results: Representative Characterization and In Vitro MCP-1 PAM Analyses
  • 07:18Conclusion

Summary

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This paper presents a method involving the synthesis and characterization of monocyte-targeting peptide amphiphile micelles and the corresponding assays to test for biocompatibility and ability of the micelle to bind to monocytes.

Tags

Peptide AmphiphileMonocyte-targetingAtherosclerosisImagingSynthesisMCP-1PlaqueCardiovascularDiagnosisAutomated Peptide SynthesisCleavage

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