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Bioengineering

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JoVE Journal Bioengineering
Synthesis of Monocyte-targeting Peptide Amphiphile Micelles for Imaging of Atherosclerosis
 

Synthesis of Monocyte-targeting Peptide Amphiphile Micelles for Imaging of Atherosclerosis

Article DOI: 10.3791/56625-v • 08:01 min • November 17th, 2017
November 17th, 2017 •
1, 1, 1
1Department of Biomedical Engineering, University of Southern California

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This paper presents a method involving the synthesis and characterization of monocyte-targeting peptide amphiphile micelles and the corresponding assays to test for biocompatibility and ability of the micelle to bind to monocytes.

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Keywords: Peptide Amphiphile Monocyte-targeting Atherosclerosis Imaging Synthesis MCP-1 Plaque Cardiovascular Diagnosis Automated Peptide Synthesis Cleavage
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