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In Vivo Gene Transfer to the Rabbit Common Carotid Artery Endothelium
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In Vivo Gene Transfer to the Rabbit Common Carotid Artery Endothelium

In Vivo Gene Transfer to the Rabbit Common Carotid Artery Endothelium

DOI:
10.3791/56982-v

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10:18 min

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May 06, 2018

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, ,
1Department of Medicine,University of Washington

Chapters

  • 00:04Title
  • 01:02Rabbit Common Carotid Artery Gene Transfer
  • 08:17Results: Representative Endothelial Transgene Analyses
  • 09:17Conclusion

Summary

Automatic Translation

Automatic Translation

This method is to introduce a transgene into the endothelium of rabbit carotid arteries. Introduction of the transgene allows the assessment of the biological role of the transgene product either in normal arteries or disease models. The method is also useful for measuring activity of DNA regulatory sequences.

Tags

In Vivo Gene TransferRabbit Common Carotid ArteryEndotheliumVascular BiologyGene TherapyTransgene ExpressionSurgical ProcedureDissectionCarotid ArteryLigationMicroscope

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