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小鼠饮酒模型在酒精中毒药物治疗发展中的应用: 黑暗中的饮酒和两瓶选择

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Medicine

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JoVE Journal Medicine

Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice

Please note that all translations are automatically generated. Click here for the English version.

小鼠饮酒模型在酒精中毒药物治疗发展中的应用: 黑暗中的饮酒和两瓶选择

DOI:

10.3791/57027-v

•

07:31 min

•

January 07, 2019

•

Nhat Huynh*¹, Natalie M Arabian*¹, Liana Asatryan, Daryl L Davies

¹Titus Family Department of Clinical Pharmacy and Pharmaceutical Economics & Policy, School of Pharmacy,University of Southern California

Chapters

00:04Title
00:38Experimental Setup and Animal Habituation
02:0224-Hour Two Bottle Choice
03:50Drinking in the Dark
05:33Results: Results for Two Bottle Choice and Drinking in the Dark
07:05Conclusion

Summary

Automatic Translation

酒精使用障碍 (aud) 是一个主要的国家健康问题, 需要开发更有效的治疗方法来抵消这些病人群体的需求。为此, 下面的协议使用两个简单的啮齿类动物饮酒模型来评估铅抗酒精化合物的临床前疗效。

Tags

Murine Drinking Models Alcoholism Pharmacotherapies Drinking In The Dark Two-bottle Choice Alcohol Use Disorder Anti-alcohol Drug Rodent Models Neurobiology Serological Pipette Shrink Wrap Single Housing Ethanol Access Two-bottle Choice Drinking In The Dark

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