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1Collaboration for Organ Perfusion, Protection, Engineering and Regeneration (COPPER) Lab, Division of Transplant, Department of Surgery, Comprehensive Transplant Center,Ohio State University Wexner Medical Center, 2Department of Surgery, Division of Transplant,Ohio State University Wexner Medical Center, 3Department of Surgery, Division of CardioThoracic Surgery,Ohio State University Wexner Medical Center, 4Department of Medicine,Ohio State University Wexner Medical Center
Chapters
- 00:04Title
- 00:36Preparation of the Portal Vein Cuff and Bile Duct Cannula
- 01:20Liver Procurement Procedure
- 05:24Ex Vivo Normothermic Liver Perfusion
- 06:58Results: Analysis of Tissue Damage in Base Perfusate-only and Base Perfusate and Plus PEG-CAT Groups
- 07:56Conclusion
Hay una escasez de donantes de hígado significativa, y se han ampliado los criterios de los donantes de hígado. Perfusión normotérmica ex vivo hígado (NEVLP) ha sido desarrollada para evaluar y modificar la función del órgano. Este estudio muestra un modelo de rata de NEVLP y pone a prueba la capacidad de pegilado-catalasa, para mitigar la lesión hepática de preservación.
