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Udnyttelse af ultralyd guidede væv-instrueret cellulære Implantation for etablering af biologisk relevante metastatisk Tumor Xenografts
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1Departments of Surgery, C.S Mott Children’s and Women’s Hospital,The University of Michigan Medical School, 2Departments of Pathology, C.S Mott Children’s and Women’s Hospital,The University of Michigan Medical School, 3Unit for Laboratory Animal Medicine,The University of Michigan Medical School, 4Departments of Radiology, C.S Mott Children’s and Women’s Hospital,The University of Michigan Medical School, 5Departments of Pediatrics, C.S Mott Children’s and Women’s Hospital,The University of Michigan Medical School
Chapters
- 00:04Title
- 01:13Preparation of Primary Patient-derived Tumor Cells
- 03:29Ultrasound Guided Implantation
- 05:48Results: In Vivo Ultrasound Imaging of Tumor Engraftment and Growth
- 07:22Conclusion
Vi præsenterer her, en protokol for at udnytte ultralydsvejledt injektion af neuroblastoma (NB) og Ewings sarkom (ES) celler (etableret cellelinjer og patient-afledte tumorceller) på biologisk relevante websteder til at oprette pålidelige prækliniske modeller for kræft forskning.
