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Evaluating the Role of Mitochondrial Function in Cancer-related Fatigue
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Cancer Research
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JoVE Journal Cancer Research
Evaluating the Role of Mitochondrial Function in Cancer-related Fatigue

Evaluating the Role of Mitochondrial Function in Cancer-related Fatigue

DOI:
10.3791/57736-v

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08:56 min

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May 17, 2018

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, , ,
1National Institute of Nursing Research,National Institutes of Health

Chapters

  • 00:04Title
  • 01:26Mitochondrial Function Measurement and Clinical Sample Preparation (Day 1 and 2 of the Experiment)
  • 02:16Mitochondrial Function Measurement
  • 05:21Normalization of Mitochondrial Functional Data
  • 06:13Results: Use of Mito Stress Test to Diagnose Dysfunction in Fatigued Cancer Patients
  • 07:34Conclusion

Summary

Automatic Translation

Automatic Translation

Our goal was to develop a practical protocol to evaluate mitochondrial dysfunction associated with fatigue in cancer patients. This innovative protocol is optimized for clinical use involving only standard phlebotomy and basic laboratory procedures.

Tags

Keywords: Mitochondrial DysfunctionCancer-related FatigueRadiation TherapySupportive Cancer CareRespiratory InhibitorsPBMCAssay MediaCell ConfluencyNon-CO2 Incubator

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