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Assessment of Respiratory Function in Conscious Mice by Double-chamber Plethysmography
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JoVE Journal Medicine
Assessment of Respiratory Function in Conscious Mice by Double-chamber Plethysmography

Assessment of Respiratory Function in Conscious Mice by Double-chamber Plethysmography

DOI:
10.3791/57778-v

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08:58 min

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July 10, 2018

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, , , , , , ,
1Institut Universitaire de Cardiologie et de Pneumologie de Québec,Université Laval, 2SCIREQ Scientific Respiratory Equipment Inc.

Chapters

  • 00:04Title
  • 00:54Equipment Preparation
  • 03:33Animal Preparation
  • 04:58Lung Function Measurements
  • 06:31Results: Respiratory Function in BALB/c mice and C57BL/6 mice
  • 08:13Conclusion

Summary

Automatic Translation

Automatic Translation

The objective of the present article is to provide a detailed description of the recommended procedures to evaluate respiratory function in conscious mice by double-chamber plethysmography.

Tags

Keywords: Respiratory FunctionDouble-chamber PlethysmographyConscious MiceRespiratory ResearchSafety PharmacologyDrug DevelopmentBreathing PatternAirway ObstructionCalibrationBias Flow GeneratorThoracic ChamberCalibration ToolThoracic Flow SignalSyringe

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